Interventional psychiatry uses closely supervised treatments, such as TMS, Spravato® and ketamine, when medication and therapy have not been enough. Our board-certified psychiatrists near Union Square evaluate you, recommend the option that fits and oversee every session.
Medically reviewed by Yuli Fradkin, MD, board-certified psychiatrist · Last reviewed October 2026
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Psychiatrists, 25+ years
THE BASICS
Most psychiatric care relies on medication and talk therapy. Interventional psychiatry adds treatments that act on the brain more directly: brain stimulation with transcranial magnetic stimulation (TMS), and medicines that work on the brain's glutamate system, such as esketamine and ketamine, given under monitoring in the clinic.
These treatments are usually considered after depression has not responded to at least two antidepressants. The National Institute of Mental Health describes TMS and other brain stimulation therapies as options when other treatments have not worked.
What sets interventional psychiatry apart is the setting. Every treatment happens in our office, with a psychiatrist setting the plan, a clinical team monitoring you, and standard rating scales tracking whether it is working.
TMS devices are FDA-cleared, and Spravato is an FDA-approved medicine. IV and IM ketamine for depression are off-label, and we explain what that means before you start.
TREATMENTS
We offer the three main interventional treatments for depression in one office, so your psychiatrist can recommend what suits you rather than whatever is available.
BRAIN STIMULATION
Magnetic pulses stimulate the brain area involved in mood. FDA-cleared for depression that has not responded to antidepressants. Sessions take about 20-30 minutes, with no anesthesia. About TMS therapy.
NASAL SPRAY
An FDA-approved nasal spray for treatment-resistant depression, taken in our REMS-certified office with at least two hours of monitoring. About Spravato in NYC.
IV / IM
Ketamine given by infusion or injection, used off-label for depression and usually self-pay. You are monitored throughout and need a ride home. About ketamine therapy.
WHO IS REFERRED
Most of our patients are adults with major depression that has not improved after two or more antidepressants taken at a proper dose for long enough. Some come to us on their own after reading about TMS or Spravato. Others are referred by their psychiatrist, therapist or primary care doctor.
We also see people who responded to medication but could not tolerate the side effects, people with depression and significant anxiety, and people who would rather not add more medicines. Everyone has a full evaluation first, because these treatments are not right for everyone.
Clinicians can refer patients through our provider referral page. With the patient's consent, we keep the referring clinician updated and coordinate ongoing care with them.
AT A GLANCE
The treatments work in different ways and are regulated differently. Here is what each one does.
Compare brain stimulation options in our TMS vs ECT guide, or see how TMS, Spravato and ketamine compare for treatment-resistant depression.
WORKING TOGETHER
Send a referral or ask your patient to contact us. We handle insurance checks and prior authorization.
With consent, we send updates after the evaluation and at the end of a treatment course.
Many patients keep their current medicines during treatment. Any change is discussed with you and your prescriber.
You keep seeing your therapist. Therapy and interventional treatment often work well together.
HOW IT WORKS
STEP 1
We hear what you have tried and verify your insurance at no cost.
STEP 2
A board-certified psychiatrist confirms the diagnosis and checks which treatments are safe for you.
STEP 3
We recommend TMS, Spravato or ketamine, explain why, and handle prior authorization where needed.
STEP 4
Your treatment starts, and we measure your progress regularly against your starting point.
MEASUREMENT-BASED CARE
Before treatment, you complete standard questionnaires, such as the PHQ-9 for depression, so we have a clear starting point.
We repeat the questionnaires at set points and ask about side effects, sleep and day-to-day life.
We compare your scores with your baseline and decide with you whether to stop, continue or change approach.
We check in after treatment ends and plan maintenance if symptoms start to return.
SAFETY
TMS is given while you are awake and alert. The most common side effects are scalp discomfort and headache in the first sessions. Seizures are rare, and we screen for risk factors before you start.
Spravato and ketamine can cause dissociation, dizziness, nausea and a temporary rise in blood pressure, so we check your blood pressure and monitor you after each dose. Spravato is only given under the FDA-required SPRAVATO REMS program, with at least two hours of monitoring.
Every treatment plan is set and supervised by a board-certified psychiatrist.
Board-certified psychiatrists with decades of experience in treatment-resistant depression, TMS and anxious depression.
Board-Certified Psychiatrist · 25+
Years Experience
I founded Village TMS because so many of my patients had been failed by
standard treatment paths. My approach is unhurried, evidence-driven, and centred on what each person actually needs to feel like themselves again.
Board-Certified Psychiatrist · 15+ Years Experience
I came to TMS after watching patients
cycle through medications that didn't fit them. My focus is precision, matching the right protocol to the right person, and adjusting as we go.
Psychotherapist & Coach ·
Couples Therapy
I help adults and couples build self-awareness and deepen relationships. My work is grounded in Gestalt therapy and informed by EMDR, mindfulness, and transpersonal psychology. I combine deep emotional exploration with practical tools, working in a warm, collaborative space where clients feel genuinely seen and supported.
Everything you need to know before your free consultation.
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All treatments take place at our office at 80 Fifth Avenue, Suite 1405, at 14th Street. Patients come to us from across Manhattan, Brooklyn, Queens and northern New Jersey.
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