Physician-led ketamine therapy in Manhattan, for treatment-resistant depression, anxiety, OCD, PTSD, and more. IV ketamine, IM injections, and FDA-approved Spravato®, each delivered and monitored by board-certified psychiatrists.
Spravato (esketamine) is a Schedule III (CIII) prescription nasal spray, FDA-approved for adults with treatment-resistant depression and for major depressive disorder with acute suicidal thoughts, and it is given only in a certified, supervised setting.
Or call (646) 817-2835 — speak with our team now
Rated 5.0
On Google reviews
FDA-Cleared
Safe & evidence-based
In-Network
Aetna, BCBS, Cigna, United
Board-Certified
Psychiatrists, 25+ years
verified Google Reviews
See all reviews →
Dr Fradkin helped me with treatment-resistant depression using TMS.
Valery Dinner Verified Google ReviewI had a great experience at the Village TMS Center for Autism and Depression. The staff is very kind, professional, and truly cares about their patients. They take the time to listen and explain the treatment process clearly.
kibriyo komilova Verified Google ReviewMy son just finished TMS therapy with Village Group Medical. I am pleased to mention pleasant and welcoming atmosphere of this office. It helped my son relax and agree to undergo the therapy.
Yelena Haskin Verified Google ReviewVery professional and caring team. I enjoyed learning more about this solution and was pleased with the provided service!
Raul Ifraimov Verified Google ReviewTMS session with George went great. Even though I just started and it’s a new experience for me, a cautious supervision and guidance of the specialist helps to get through. I had all my questions being answered before the procedure. Will come again!
Ekaterina Kokovikhina Verified Google ReviewJust had my first TMS session. Feeling great!
Sofia Dro Verified Google ReviewDr Fradkin helped me with treatment-resistant depression using TMS.
Valery Dinner Verified Google Review
Ketamine assisted therapy is a modern psychiatric treatment that uses low,
carefully controlled doses of ketamine to relieve symptoms of depression and other mood disorders. Originally introduced decades ago as a safe surgical anaesthetic, ketamine has since been studied extensively for its effects on mood. At our Manhattan clinic, every dose is administered and monitored by board-certified psychiatrists in a calm, clinical setting.
What makes ketamine different is how it works in the brain. Most
antidepressants target the serotonin system and can take four to six weeks tomake a difference. Ketamine acts on the brain's glutamate and NMDA
receptor system, which is believed to promote neuroplasticity, the brain's
ability to form new neural connections. This mechanism is one reason
ketamine can sometimes help people who have not responded to traditional
medications.
For New Yorkers across Manhattan, Brooklyn, Queens, and northern New
Jersey, Spravato NYC offers another evidence-
based option when standard treatments have fallen short. It is not a quick fix
or a take-home prescription. It is a supervised medical treatment delivered aspart of a personalised plan.
Ketamine's antidepressant effects have been studied in numerous peer-
reviewed trials, and esketamine (Spravato®) is FDA-approved for treatment-resistant depression.
We offer IV, IM, and Spravato under one roof, so your psychiatrist can match the
right approach to your situation.
IV INFUSION
Our clinic provides ketamine therapy through carefully monitored IV ketamine infusions. This treatment allows medication to enter the bloodstream quickly and may help patients experiencing resistant depression or severe depressive symptoms.
Nasal Spray
For patients seeking Spravato NYC, our Certified Spravato clinic administers FDA-approved esketamine nasal spray for adults with treatment-resistant depression. Spravato treatment occurs in a certified treatment center and follows the official Risk Evaluation and Mitigation Strategy required in the United States.
IM INJECTION
Intramuscular ketamine injections provide another option for individuals exploring ketamine treatment for mood disorders or resistant depression. These treatments allow the clinical team to tailor care to specific treatment goals while supporting long-term stability between sessions.
Spravato® (esketamine) is a nasal spray derived from ketamine. It is FDA-approved for treatment-resistant depression in adults, used together with an oral antidepressant. It is also approved for depressive symptoms in adults with major depressive disorder who have acute suicidal thoughts or behaviour.
Because of its profile, Spravato must be administered in a healthcare setting certified under the FDA's REMS (Risk Evaluation and Mitigation Strategy) program. After each dose, patients are monitored on-site for at least two hours and cannot drive for the rest of that day, so you will need to arrange a ride home.
This in-clinic model is also why Spravato NYC is more frequently covered by insurance than IV or IM ketamine, which are typically used off-label. Candidates are generally adults whose depression has not responded adequately to other antidepressants. A psychiatrist will onfirm whether it is appropriate for you.
A side-by-side look to help you and your psychiatrist choose the right path.
| Treatment | How it's given |
Typical session length |
FDA status |
Insurance likelihood |
Best suited for |
|---|---|---|---|---|---|
|
IV Infusion |
Slow intravenous drip, in-clinic |
~40 min, plus
monitoring |
Off-label for
mood disorders |
Often self-pay / out-of-network |
Rapid relief, treatment-resistant depression, certain chronic pain |
|
IM Injection |
Intramuscular injection, in-clinic |
~40 min, plus
monitoring |
Off-label for
mood disorders |
Usually self-pay |
A simpler alternative to IV for some patients |
|
Spravato® Nasal Spray |
Self-administered nasal spray under supervision |
Dose plus ~2 hr monitoring |
FDA-approved for TRD |
More often covered by insurance |
Treatment-resistant depression, alongside an oral antidepressant |
IV and IM ketamine are used off-label and are frequently self-pay. Spravato is FDA-approved and, because it is given in-clinic, is more often covered. We verify your specific coverage for free.
Some patients report meaningful symptom improvement within hours or days of treatment. Ketamine works through the brain’s glutamate system and can help restore pathways associated with mood regulation.
Research shows ketamine interacts with NMDA receptors, which influence neural communication in the brain. This mechanism differs from traditional antidepressants and may provide relief when conventional medications have failed.
All treatments occur in a clinical setting under the supervision of a healthcare provider. Our board-certified psychiatrist and clinical team follow strict safety protocols and evaluate medical history to identify potential side effects or underlying medical conditions.
Many patients benefit from combining ketamine therapy with TMS therapy, talk therapy, or medication management. A personalized care plan helps support long-term well-being and sustainable progress.
We review your history, answer
your questions, and verify
insurance coverage at no cost.
Choose from IV, SPRAVATO®, or IM treatments, customized by our healthcare providers for your needs and treatment effects.
You're cared for in a
comfortable setting with vitals
tracked throughout each
session.
Post-treatment, our therapists help you apply insights from the ketamine experience to improve thought patterns and support lasting recovery.
You begin with a consultation. We take a careful medical and psychiatric history, discuss your goals, and design a personalised protocol. We also verify your insurance coverage and answerany questions so you feel informed before anything begins.
You're seated comfortably in a quiet, monitored room. A typical session lasts around 40 minutes,
with vitals tracked throughout. Many patients notice a mild, transient sense of dissociation, a
floating or dreamlike feeling, that fades as the session ends. Our team is present the entire time.
Because of the temporary effects, you should not drive on a treatment day, so arrange a ride
home in advance. Many patients benefit from optional integration or therapy support to help
translate the experience into lasting change.
Treatment usually starts with an initial series of sessions, followed by maintenance visits as
clinically indicated. Your psychiatrist tracks your response and adjusts the plan over time, rather
than following a fixed one-size-fits-all schedule.
In recent years, studies have highlighted the effectiveness of ketamine for
psychiatric disorders such as major depressive disorder, bipolar disorder,
and post-traumatic stress disorder. By targeting glutamate pathways,
ketamine promotes symptom reduction, reduces suicidal ideation,
and supports a healthier response to stress.
We use low-dose protocols to ensure safety and minimize dissociative effects.
While brief lightheadedness may occur, most patients find it subsides within minutes. Each session is conducted in a calm clinical setting, in the middle
of Manhattan, by licensed healthcare professionals who track your vital signs
and adjust your treatment plan for optimal comfort.
Because Spravato is a controlled medication, it is dispensed only through a certified treatment center under the FDA's Risk Evaluation and Mitigation Strategy (REMS) program. Before treatment begins, you receive the Important Safety Information, the Medication Guide, and the Full Prescribing Information, so you and your family understand both the common and the more serious side effects. Our care team screens for conditions such as high blood pressure, breathing problems, and vascular conditions before your first session, and monitors your vital signs during the two-hour observation period after each dose.
All sessions are monitored by board-certified psychiatrists. Screening determines whether ketamine is appropriate for you.
TMS & Ketamine therapy and evidence-based care for:
Including treatment-resistant depression —
the primary FDA-approved use of TMS.
FDA-approved deep TMS protocol for OCD
when therapy alone hasn't worked.
FDA-approved for depression with co-
occurring anxiety symptoms.
FDA-approved deep TMS protocol for
nicotine addiction.
Board-certified psychiatrists with decades of experience treating depression, OCD,
and anxiety.
I founded Village TMS because so many of my patients had been failed by
standard treatment paths. My approach is unhurried, evidence-driven, and centred on what each person actually needs to feel like themselves again.
I came to TMS after watching patients
cycle through medications that didn't fit them. My focus is precision, matching the right protocol to the right person, and adjusting as we go.
I help adults and couples build self-awareness and deepen relationships. My work is grounded in Gestalt therapy and informed by EMDR, mindfulness, and transpersonal psychology. I combine deep emotional exploration with practical tools, working in a warm, collaborative space where clients feel genuinely seen and supported.
Everything you need to know before your free consultation.
Spravato therapy is a prescription medicine derived from ketamine and approved for adults with treatment-resistant depression and major depressive disorder. It is administered as a nasal spray in a certified treatment center and must be used under medical supervision.
Spravato works differently than traditional antidepressants. Instead of focusing mainly on serotonin, the medication interacts with NMDA receptors in the brain’s glutamate system. This pathway helps regulate neural communication associated with mood and emotional processing.
Many patients with resistant depression have tried multiple oral antidepressant medications without success. In those cases, Spravato provides a new option for treatment that may help restore mood regulation and reduce severe depressive symptoms.
Individuals who may qualify for Spravato NYC treatment typically have a diagnosis of major depressive disorder and have not responded to several traditional antidepressants or conventional medications.
During the initial consultation, a board-certified psychiatrist or healthcare professional reviews your medical history, current symptoms, and previous treatment outcomes. The evaluation helps determine whether Spravato therapy aligns with your treatment goals.
Patients experiencing severe depression, suicidal thoughts, or persistent depressive symptoms despite trying different antidepressants may be considered eligible. The evaluation process helps ensure the treatment is appropriate for each person’s mental health conditions and overall medical safety.
The Spravato treatment process begins with a psychiatric evaluation and review of your medical history. If approved, the patient attends treatment sessions at a certified treatment center where the medication is administered.
During each session, the patient self-administers the nasal spray under the supervision of a healthcare provider. After receiving the first dose, patients remain in the clinic for monitoring while the clinical team checks vital signs and watches for possible side effects.
Observation typically lasts around two hours to ensure safety. Because Spravato can temporarily affect perception or blood pressure, patients are not allowed to drive after treatment and should arrange transportation home.
Most patients begin with a structured treatment schedule consisting of weekly sessions during the first phase of treatment. This initial stage allows the care team to evaluate how the medication affects depressive symptoms and mood regulation.
After the initial treatment course, many patients transition into a maintenance phase where sessions occur less frequently. The exact schedule depends on symptom improvement, medical advice, and overall treatment goals.
A personalized care plan helps ensure patients receive the appropriate number of sessions while maintaining long-term stability throughout their mental health journey.
Many insurance providers in the United States provide insurance coverage for Spravato therapy when certain criteria are met. Patients must typically show a history of treatment-resistant depression and documented use of multiple traditional antidepressants.
Our clinic assists patients in verifying insurance coverage and determining whether treatment may be covered by insurance, including plans such as UnitedHealthcare. The clinic staff can also help estimate out-of-pocket costs and explain coverage details before treatment begins.
Understanding insurance benefits before starting therapy allows patients to focus on treatment rather than financial uncertainty.
Yes. Many patients receive Spravato therapy alongside other evidence-based treatments. Combining Spravato with Transcranial Magnetic Stimulation, psychotherapy, or medication management can help support more consistent improvement.
Some individuals also benefit from additional ketamine therapy approaches or talk therapy that address underlying behavioral health factors contributing to depression symptoms.
A comprehensive care plan developed by the clinical team helps patients pursue long-term stability while addressing the root causes of mood disorders.
They are related but not the same. Spravato is the FDA-approved esketamine nasal spray, self-administered under supervision in our office. IV ketamine is delivered intravenously and is used off-label for depression. Both act on the brain’s NMDA receptor and glutamate system to support new neural pathways and faster mood improvement, but they differ in how they are given, how they are covered by insurance (Spravato is more often covered because it is FDA-approved and given in-clinic), and which patients they suit. Your care team helps determine the best fit based on your symptoms, medication history, and any conditions such as bipolar disorder.
The first step is scheduling an initial consultation with a healthcare professional experienced in treating treatment-resistant depression. During this visit, the provider reviews medical history, current symptoms, and treatment goals.
If the patient qualifies, the clinic schedules the first treatment session and develops a personalized treatment course tailored to the patient’s needs.
For individuals searching online for Spravato NYC, this consultation can be the beginning of a new treatment path toward improved mental health, symptom relief, and long-term emotional stability.
· 5 min read
· 5 min read
· 5 min read
· 5 min read
· 5 min read
We proudly serve patients throughout Manhattan and the greater New York area.
Greenwich Village ·
Chelsea · West Village ·
East Village · SoHo ·
Tribeca · Flatiron ·
Midtown
Williamsburg · Brooklyn
Heights · Park Slope ·
Long Island City · Astoria
· Forest Hills
Hoboken · Jersey City ·
Weehawken · Edgewater
· Fort Lee
