Ketamine NYC: a new hope when antidepressants haven't worked

Physician-led ketamine for anxiety NYC, in Manhattan, for treatment-resistant depression, PTSD, and more. IV ketamine, IM injections, and FDA-approved Spravato®, each delivered and monitored by board-certified psychiatrists.

Or call (646) 817-2835 — speak with our team now

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FDA-Cleared

Safe & evidence-based

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Aetna, BCBS, Cigna, United

Board-Certified

Psychiatrists, 25+ years

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INSIGHTS

What Is Ketamine Treatment NYC?

Ketamine assisted therapy is a modern psychiatric treatment that uses low,
carefully controlled doses of ketamine to relieve symptoms of depression and other mood disorders. Originally introduced decades ago as a safe surgical anaesthetic, ketamine has since been studied extensively for its effects on mood. At our Manhattan clinic, every dose is administered and monitored by board-certified psychiatrists in a calm, clinical setting.

What makes ketamine different is how it works in the brain. Most
antidepressants target the serotonin system and can take four to six weeks tomake a difference. Ketamine acts on the brain's glutamate and NMDA
receptor system, which is believed to promote neuroplasticity, the brain's
ability to form new neural connections. This mechanism is one reason
ketamine can sometimes help people who have not responded to traditional
medications.

For New Yorkers across Manhattan, Brooklyn, Queens, and northern New
Jersey, ketamine for anxiety in New York City offers another evidence-
based option when standard treatments have fallen short. It is not a quick fix
or a take-home prescription. It is a supervised medical treatment delivered aspart of a personalised plan.

Science-Backed

Ketamine's antidepressant effects have been studied in numerous peer-
reviewed trials, and esketamine (Spravato®) is FDA-approved for treatment-resistant depression.

Ketamine treatment near me

YOUR OPTIONS

Three Evidence-Based Ketamine
Treatments

We offer IV, IM, and Spravato under one roof, so your psychiatrist can match the
right approach to your situation.

IV INFUSION

IV Ketamine Infusions

Intravenous ketamine infusions work directly on the glutamate and NMDA system, with some patients improving within days. Each 40-minute session is monitored for heart rate and blood pressure to ensure safety.

Nasal Spray

Spravato® (Esketamine)

FDA-approved alternative for treatment-resistant depression, providing quick relief with minimal downtime. Our trained professionals supervise each session to optimize dosing and monitor your ital signs.

IM INJECTION

Intramuscular (IM) Injections

A convenient short-term solution for those seeking effective results with minimal clinic time. These low-dose injections offer lasting anxiolytic effects while supporting continued stability between sessions.

Ready to see if ketamine treatment near me is right for you?

FDA-APPROVED OPTION

Spravato® (Esketamine): What You Should Know

Spravato® (esketamine) is a nasal spray derived from ketamine. It is FDA-approved for treatment-resistant depression in adults, used together with an oral antidepressant. It is also approved for depressive symptoms in adults with major depressive disorder who have acute suicidal thoughts or behaviour.

Because of its profile, Spravato must be administered in a healthcare setting certified under the FDA's REMS (Risk Evaluation and Mitigation Strategy) program. After each dose, patients are monitored on-site for at least two hours and cannot drive for the rest of that day, so you will need to arrange a ride home.

This in-clinic model is also why Spravato is more frequently covered by insurance than IV or IM ketamine, which are typically used off-label. Candidates are generally adults whose depression has not responded adequately to other antidepressants. A psychiatrist will onfirm whether it is appropriate for you.

Spravato at a glance

CLEAR COMPARISON

IV Ketamine vs IM vs Spravato — How
They Compare

A side-by-side look to help you and your psychiatrist choose the right path.

Treatment How it's given Typical session
length
FDA status Insurance
likelihood
Best suited for
IV Infusion
Slow intravenous drip,
in-clinic
~40 min, plus
monitoring
Off-label for
mood disorders
Often self-pay /
out-of-network
Rapid relief, treatment-resistant
depression, certain chronic pain
IM Injection
Intramuscular injection,
in-clinic
~40 min, plus
monitoring
Off-label for
mood disorders
Usually self-pay
A simpler alternative to IV for
some patients
Spravato® Nasal Spray
Self-administered nasal
spray under supervision
Dose plus ~2 hr
monitoring
FDA-approved
for TRD
More often
covered by
insurance
Treatment-resistant depression,
alongside an oral antidepressant

IV and IM ketamine are used off-label and are frequently self-pay. Spravato is FDA-approved and, because it is given in-clinic, is more often covered. We verify your specific coverage for free.

WHY PATIENTS CHOOSE US

Why Patients Choose Ketamine Therapy
At Village TMS

Rapid Relief

Rapid onset improvement within hours of treatment. Ketamine stimulates new neural connections in the brain, helping to ease both depressive symptoms and anxiety symptoms.

Science-Backed

Extensive systematic reviews and clinical trials show that ketamine works by modulating NMDA receptors and restoring balance in the glutamate system.

Comprehensive Healing

Pair ketamine treatment with cognitive behavioral therapy or mental health treatment to achieve long-term emotional stability and symptom relief.

Safe & Supervised

Our team of healthcare providers follows a proven safety protocol during every session, minimizing potential side effects and maintaining a stable safety profile. 

HOW TREATMENT FOR KETAMINE FOR ANXIETY NYC WORKS

Your Path, in Four Steps

FREE

Free Consultation

We review your history, answer
your questions, and verify
insurance coverage at no cost.

PERSONALIZED

Personalized Protocol

Choose from IV, SPRAVATO®, or IM treatments, customized by our healthcare providers for your needs and treatment effects.

MONITORED

Monitored Sessions

You're cared for in a
comfortable setting with vitals
tracked throughout each
session.

ONGOING

Integration & Follow-Up

Post-treatment, our therapists help you apply insights from the ketamine experience to improve thought patterns and support lasting recovery.

Ready to see if Ketamine for Anxiety NYC is right for you?

THE PATIENT JOURNEY

What to Expect During Treatment

Before

You begin with a consultation. We take a careful medical and psychiatric history, discuss your goals, and design a personalised protocol. We also verify your insurance coverage and answerany questions so you feel informed before anything begins.

During

You're seated comfortably in a quiet, monitored room. A typical session lasts around 40 minutes,
with vitals tracked throughout. Many patients notice a mild, transient sense of dissociation, a
floating or dreamlike feeling, that fades as the session ends. Our team is present the entire time.

After

Because of the temporary effects, you should not drive on a treatment day, so arrange a ride
home in advance. Many patients benefit from optional integration or therapy support to help
translate the experience into lasting change.

Course of Care

Treatment usually starts with an initial series of sessions, followed by maintenance visits as
clinically indicated. Your psychiatrist tracks your response and adjusts the plan over time, rather
than following a fixed one-size-fits-all schedule.

Ready to see if Ketamine for Anxiety is right for you?

HONEST ANSWERS

Is Ketamine for Anxiety NYC Safe?
Side-Effects & Monitoring

In recent years, studies have highlighted the effectiveness of ketamine for
psychiatric disorders such as major depressive disorder, bipolar disorder,
and post-traumatic stress disorder. By targeting glutamate pathways,
ketamine promotes symptom reduction, reduces suicidal ideation,
and supports a healthier response to stress.


We use low-dose protocols to ensure safety and minimize dissociative effects.
While brief lightheadedness may occur, most patients find it subsides within minutes. Each session is conducted in a calm clinical setting, in the middle
of Manhattan, by licensed healthcare professionals who track your vital signs
and adjust your treatment plan for optimal comfort.

Common, temporary effects

All sessions are monitored by board-certified psychiatrists. Screening determines whether ketamine is appropriate for you.

Conditions We Treat

TMS & Ketamine therapy and evidence-based care for:

Major Depressive Disorder

Including treatment-resistant depression —
the primary FDA-approved use of TMS.

More about depressive disorder →

Obsessive-Compulsive Disorder

FDA-approved deep TMS protocol for OCD
when therapy alone hasn't worked.

More about OCD →

Anxious Depression

FDA-approved for depression with co-
occurring anxiety symptoms.

More about anxious depression →

PTSD

Evidence-based TMS protocols for trauma-
related symptoms.

More about ptsd →

ADHD (Adjunct Care)

Supportive treatment alongside standard
ADHD care.

More about adhd →

Smoking Cessation

FDA-approved deep TMS protocol for
nicotine addiction.

More about smoking cessation →

Meet Your Care Team

Board-certified psychiatrists with decades of experience treating depression, OCD,
and anxiety.

Dr. Yuli Fradkin, MD

Board-Certified Psychiatrist · 25+
Years Experience

I founded Village TMS because so many of my patients had been failed by
standard treatment paths. My approach is unhurried, evidence-driven, and centred on what each person actually needs to feel like themselves again.

Dr. Elena Bruck, MD

Board-Certified Psychiatrist · 15+ Years Experience

I came to TMS after watching patients
cycle through medications that didn't fit them. My focus is precision, matching the right protocol to the right person, and adjusting as we go.

Sofia Dro, MA

Psychotherapist & Coach ·
Couples Therapy

I help adults and couples build self-awareness and deepen relationships. My work is grounded in Gestalt therapy and informed by EMDR, mindfulness, and transpersonal psychology. I combine deep emotional exploration with practical tools, working in a warm, collaborative space where clients feel genuinely seen and supported.

Common Questions About
Ketamine For Anxiety NYC

Everything you need to know before your free consultation.

What is ketamine therapy?

Ketamine therapy is the clinical, medically supervised use of ketamine to treat mental health conditions, most often treatment-resistant depression, PTSD, and anxiety disorders. Unlike most antidepressants, which act on serotonin and can take four to six weeks to work, ketamine works through the brain’s glutamate system. At Village TMS it is given as an IV infusion, an IM injection, or FDA-approved Spravato nasal spray, always under psychiatrist supervision in our Manhattan clinic. A typical session runs 40 to 60 minutes, and many patients notice a lift in mood within about a day of their first treatment.

How does ketamine treatment work?

Ketamine for anxiety NYC targets NMDA receptors and activates the glutamate system, encouraging new neural pathways that regulate mood disorders and reduce anxiety symptoms. This mechanism helps patients find relief faster than with traditional antidepressants or selective serotonin reuptake inhibitors.

How soon will I feel the results?

Many patients notice a significant reduction in symptoms within hours of their first single dose. The rapid onset of relief makes ketamine a preferred option for those facing treatment-resistant depression or severe anxiety that hasn’t improved with other treatment options.

Is ketamine treatment safe?

Yes. When provided under medical supervision, ketamine for anxiety NYC has a proven safety profile supported by double-blind and randomized controlled trial data. Our staff monitors your heart rate, blood pressure, and comfort throughout your session.

What conditions does ketamine therapy help treat?

Ketamine can support patients with generalized anxiety, panic disorder, social anxiety, and refractory anxiety disorders, as well as post-traumatic stress disorder (PTSD), major depression, and treatment-resistant symptoms when standard treatment has not brought enough relief.

How long do the effects of ketamine last?

The anxiolytic effects of a single treatment may last several weeks. Maintenance sessions are available for sustained results and long-term mood stability.

Can I combine ketamine therapy with other treatments?

Absolutely. Many patients combine ketamine infusion therapy with behavioral therapy or cognitive behavioral therapy for the best results. This combined approach strengthens neural pathways and promotes sustainable improvement.

What are the potential side effects?

Temporary dissociative effects, lightheadedness, or mild blood pressure increases may occur but fade quickly. All treatment sessions are monitored in a professional healthcare setting to minimize risks and ensure comfort.

Who is a good candidate for ketamine for anxiety NYC?

Individuals who have not responded to traditional treatments or have treatment-resistant depression or treatment-resistant anxiety may benefit from ketamine therapy. A review of your medical conditions and treatment history helps determine suitability.

Can ketamine help with PTSD?

Ketamine is used off-label for bipolar depression, it is not FDA-approved specifically for bipolar, and IV ketamine is generally not covered by insurance. Spravato (esketamine) is FDA-approved, but for treatment-resistant depression, not bipolar. Off-label use is legal and common in psychiatry when supervised by a qualified physician. We are clear about costs and coverage during your consultation so there are no surprises.

Is ketamine therapy addictive?

When administered in a clinical setting and at low doses, ketamine poses no addiction risk. Our clinicians use controlled dosing to ensure therapeutic benefit without dependency.

How do I start my treatment journey?

Your first step is to schedule a free consultation at Village TMS. We’ll review your medical history, evaluate your symptoms, and create a customized treatment plan that supports healing and improved quality of life.

Still have questions? We're here to help.

Or call (646) 817-2835

INSIGHTS

Learn More About Ketamine & Mental
Health

VISIT US

Ketamine Therapy in NYC
Across The Manhattan Area

We proudly serve patients throughout Manhattan and the greater New York area.

Manhattan

Greenwich Village ·
Chelsea · West Village ·
East Village · SoHo ·
Tribeca · Flatiron ·
Midtown

Brooklyn & Queens

Williamsburg · Brooklyn
Heights · Park Slope ·
Long Island City · Astoria
· Forest Hills

New Jersey

Hoboken · Jersey City ·
Weehawken · Edgewater
· Fort Lee